Carcinogenic Hydrocarbons Essay Example for Free

Carcinogenic Hydrocarbons Essay Once in the body, they are converted into arene oxides by cytochrome P. An arene oxide is a compound in which one of the double bonds of the aromatic ring has been converted into an epoxide. The changing of the aromatic hydrocarbon into an epoxide forms a more water-soluble compound that can be eliminated from the body. Arene oxides can react in two ways. They can undergo attack by a nucleophile to form addition products or rearrange to form a phenol. Some aromatic hydrocarbons are carcinogens, meaning they can cause cancer. Investigations have shown that hydrocarbons themselves are not carcinogenic, but the carcinogens are the oxidation products of the aromatic molecules. Nucleophiles react with epoxides to form addition products. 2’-Deoxyguanosine, a component of DNA, has a nucleophilic NH? group that is known to react with certain arene oxides. Once it attaches to an arene oxide, the 2’-deoxyguanosine can no longer fit into the DNA. This results in the genetic code not being properly transcribed, which can lead to mutations that cause cancer. Arene oxides’ becoming carcinogenic depends on the rates of its two reaction pathways: rearrangement and reaction with a nucleophile. When an arene oxide rearranges, it forms phenols which are not carcinogenic. However, the formation of two addition products from nucleophilic attack by DNA can be carcinogenic. If the rate of arene oxide rearrangement is faster the nucleophilic attack by DNA, the arene oxide is harmless. If the rates are the other way around the arene oxide is likely to be carcinogenic. The rate of arene oxide rearrangement depends on the stability of the carbocation formed in the rate determining step. So, an arene oxide’s cancer causing ability depends on the stability of the carbocation. If the carbocation is stable, the rate will be faster and therefore the arene oxide is less likely to be carcinogenic. If the carbocation is unstable, the rate will be relatively slow and the arene oxide will more likely be attacked by nucleophiles. This leads to the possibility of carcinogens. After reading thoroughly through the Organic Chemistry 5th Edition book by Paula Bruice, I must agree with the investigations that have proven aromatic hydrocarbons to be non-carcinogenic. It is kind of interesting that arene oxides become carcinogenic depending on the reaction pathway it takes. I would like to know what other, if any, factors may contribute to carcinogens being formed once aromatic hydrocarbons enter the body

Ethical Implications Of Image Manipulation

Ethical Implications Of Image Manipulation There are many arguments both for and against image manipulation in the media by the public. Groups argue that image manipulation contributes to eating disorders in both women and men and a general decline in self-worth. But opposing views suggest that image manipulation is a necessity for the upkeep of our idyllic view of celebrity culture, or is a form of art. Through my research, I will look at literature that may suggest that the use of image manipulation is negatively affecting our views of society and, in turn, what positive effects it is having too. When speaking about image manipulation, we need to think of the ethics involved. In a post about the ethics of image manipulation, Lodriguss says; When we correct, manipulate and enhance images in Photoshop, we must deal with questions of both ethics and aesthetics. (Lodriguss, 2006) What is ethical and what is not in terms of image manipulation? In what way are we manipulating the images, and is this for good or bad? There are a whole host of questions that can be asked, but we must focus our attention on whom the editing is affecting. When an image is edited, we are looking at two possible audiences who could be affected by the image; the subject and the people viewing the image. These two parties will each have different views about the editing that means the moral implications become entwined. When a reader picks up a magazine, looks at a billboard advertisement of a celebritys latest perfume release, or a fashion shoot, their view of the subject is most likely skewed. The editors of these publications often embrace imaging software and its editing features to better engage their target audience, and also to assist celebrities in keeping up their perfect image. Lucy Danziger, editor-in-chief of Self Magazine, has been quoted saying Yes, of course we do post-production corrections on our images. Photoshopping is an industry standard. (The Daily Mail, 2012) This was said about an image of Kelly Clarkson that was heavily altered. It may be seen by some that the editing of the image is ethically correct as it is maintaining a positive image of the artist. We have to remember that looks sell and in the dog eat dog world that is celebrity culture, does the digital world offer a safe haven for those who may need those few extra pounds shaved off? We have seen a strong example of how digital manipulation can help those that are being edited, but what about the audience that view and interpret the images? It is quite apparent that the editors of the media publications have an agenda when it comes to image manipulation. Maximising profit. A general understanding is that the public want to see the glam and glitz that comes with the size zero celeb. Its a form of escapism in the sense that the decoders may look at a magazine front cover and get lost in its world of designer gear and pocket sized pooches. But that escape from reality is short-lived, and the effects of over exposure from these edited images can be devastating. Young girls are exposed to between 400 and 600 media images per day. (Hawkins, 2012) With such a high figure, is it any wonder that there has been an outcry from charities, that support those affected by eating disorders, to ban excessive photo manipulation? The BBC say that the media is a powerful influence and we know how vulnerable some people at risk of eating disorders can be to its visual images in particular in a quote from Susan Ringwood of B-Eat. (British Broadcasting Corporation, 2010) Charities are getting angry that the media is allowed to digitally diet celebrities with no form of ethical guidelines that they must adhere to. However change may be on the horizon. The government are currently looking at reducing the amount of editing that institutions are allowed to put out into the mainstream public. They [à ¢Ã¢â€š ¬Ã‚ ¦] want to keep computer enhancement and digital manipulation to an absolute minimum (eg red eye reduction, background lightening). (Herrin, 2011) The gov ernment have seen that the stream of unrealistic photos that plague the media is affecting the way some people view themselves, which is therefore having an effect on their own wellbeing. By creating an ethical code that institutions have to follow, they will be taking one step to safeguarding those at risk of influence. Early this year, a young 14-year-old girl named Julia Bluhm from Maine, USA, started a petition on the Internet to try and get teenage magazine Seventeen to print unedited photos of women once a month. Julia didnt think that she would get nearly the amount of signatures that she did, totalling up a staggering 84,000. This figure effectively illustrates how many young females believe that image manipulation has a negative influence on the youth of today. The magazine promises not to doctor girls body shapes or face shapes (Dieken, 2012) which means that it wont be reducing the waist size or the complexion of the young girls. Girls will now be able to read a magazine with accurate representations of their peers, even if it is only once a month. This was seen as a massive breakthrough in the media industry, with her crusade [leading] to a magazines commitment to change. (The Daily Mail, 2012) I believe that both the encoder and the decoder of media texts have valid arguments when it comes to the ethics of image manipulation. I think that the celebrity culture demands that those in the spotlight look their very best at all possible times, and the media make a positive contribution to that image remaining so. I do however believe that the repercussions of this editing take an over arching negative effect on those who view them. Young women should not have to be subjected to a bombardment of ultra skinny, perfect representations of women. If those images were mediated by the institutions to a set code of ethics, I believe that the representations of women and the ramifications would be much less negative and tarnished.

Essay --

â€Å"Demaryius Thomas is at the 20, the 10, TOUCHDOWN! The crowd goes wild! The Denver Broncos are going to the Super Bowl!† exclaimed, the newscaster. This wonderful image has been in the dreams of every Denver Broncos’ fans for over a decade. It has now become reality, for the Denver Broncos are participating in Super Bowl XLVIII. This paper’s main focus is to provide information on the Denver Broncos history, players, coaches, its super charged offense, and the Broncos’ road to the Super Bowl. According to Broncos history, the Denver Broncos first joined the National Football League (NFL) in 1960 with a dismal season winning only four out of the 14 games under the helm of Head Coach Frank Filchock. It took 17 years until the Denver Broncos made it to their first Super Bowl XII. Colorado embraced this team and nicknamed them the â€Å"Orange Crush† named after their perilous defense. Led by head coach Red Miller and quarterback Craig Morton, unfortunately they lost to the Dallas Cowboys in a 27 to 10 game. The Denver Broncos fans had to wait another 9 years for the next three Super Bowls under the direction of Head Coach Dan Reeves and with Colorado’s most iconic quarterback, John Elway in 1986, 87, and 89. Quite surprisingly, the Broncos lost all three Super Bowls (XXI, XXII, and XXIV) in the 80’s. Finally in the late 90’s John Elway near retirement led the 1997 and 1998 Broncos to their first two consecutive Super Bowl wins (XXXII and XXX III) under Head Coach Mike Shanahan. Presently, the Denver Broncos are the American Football Conference (AFC) Champions winning the game against the New England Patriots on January 19th, 2014. John Fox the 14th head coach of the Denver Broncos with a 24-year coaching career has won 112 gam... ...chdowns, nearly 4,000 receiving yards. This is his first Super Bowl appearance. Minnesotan, Eric Decker number 87 in his 4th year with the Denver Broncos scored 33 touchdowns, and 3,000 receiving yards. In week, 13 of the 2013-2014 season Decker earned the AFC Offensive Player of the Week award after scoring four touchdowns in a single game. To summarize, the Denver Broncos are on pace to becoming the best team in the history of the NFL. Consequently, on February 2nd, 2014 the Denver Broncos must face off against the Seattle Seahawks, the best team in the NFC at Super Bowl XLVIII. This highly anticipated game will decide the fate of which team can claim they are the World Champions. It will take the entire Denver Broncos team, coaches, players, and fans to conquer the mighty Seahawks and claim their prize in the history books as the best team in the world.

Impact of internet social and political Essay

The internet is less than two decades old but its impact has been felt by almost everyone in the global village. It has not only revolutionized our personal interaction habits but has also impacted greatly on other spheres of our life, most notably the economy. In many societies, the digital technology has not only influenced the political communication but also the whole political systems. Shapiro (1999) suggests that the digital technology has captured the attention of everyone from the media, government and the general public. Although the invention of the internet has brought with it some negative aspects, the digital technology has been hailed as the man’s new road to the better world. This paper will try to discuss some of the aspects of the internet that have continuously impacted on our social and political behaviours as citizens. Computers and the internet have greatly facilitated and expanded the individuals’ capacities in every sector of the society. Gurstein (2000) contends that the new ICTs have impacted almost everyone from institutions to business to organizations to the political arena. The impact has been so great that every sector of our society feels obliged to embrace the information communication technology in order to either improve the running of the government, community networking or to improve the citizen participation in the new information society. Terms such as â€Å"citizen networks†, â€Å"digital cities† or â€Å"e-governments† have become common expressions these days. They simply imply the new ways of interactions that exist between the governed and the government and new ideas regarding the metropolitan policies, through the use of electronic media (Sclove, 1995). The urban settings, built landscape as well as the social setting in our society, has undergone tremendous transformation from the last decade into the new millennium. The citizens have also not been left behind in this era of transformation. What we consider space, time, and our perception of politics as well as what we consider public or private and local or global has greatly changed. The advancement in the information communication technology has largely contributed to the changes in our cities and contemporary societies (Tsagarousianou, Tambini, & Bryan, 1998). There is a new concept that has caught on with most people in our society concerning governance. The term â€Å"electronic democracy† though has been in use since 1960s when most activists introduced a number of communication medias like free radio stations, to make the governments more accountable and responsive to its citizens, has found its way back in the advent of the internet (Sclove, 1995). Internet is currently being used to marshal grassroots groups to support a certain cause by most civil activists. There is also a growing mass of citizen initiatives that help to shape public opinion and thus influencing policies both at the national and local level. The internet therefore has greatly challenged the hitherto monopolies of the most political classes through better communication networks that have empowered the citizens to create a form of democracy in the society (Schuler, 1998). Today, many cities around the globe have created home pages in the internet and forums for interaction with their city residents. Governments around the world both at the local and national level in developed and developing nations alike, have invested in e-government projects through networks that enable citizens access to government structures, engage in online transactions or to get information on government policies. Some of these networks and sites have enable citizens to participate in most decision making regarding the management of urban habitats (Underwood, 2002). The internet has great potential to amass groups of people persuasive to certain ideologies. Many organizations now have websites which they use not only to communicate with their members but to recruit more like-minded individuals into their groups. Indeed the internet has become one of the major tools for lobbying citizens to a particular cause. Such organizations as the Internet Society and Voters Frontier Foundation have been very active in recruiting and educating the public on political issues in America (Tsagarousianou, Tambini, & Bryan, 1998). These groups have greatly contributed to the policy making processes through intensive lobbying. The internet has therefore provided a better platform for the citizens to actively participate in the political arena. This development has actually dealt a big blow to the interest group politics that have gone on over the years (Davis, 1999). The internet has impacted greatly on how we interact these days. Due to its widespread and accessibility, the information communication technology has completely changed the forms of social engagements. Today, there are numerous social networking sites that have increased the speed at which we do interact and organize our social activities. The most notable ones are MySpace and Facebook, which have simply taken the social interactions to the next level. These sites not only make it easier to keep in touch with friends and family members but enable subscribers to find other friends online. The era of information communication has ushered in a new way of keeping contacts with others no matter the distance between us. In a nutshell, the internet has reduced the world to a global village where everyone can be reached simply by a few clicks of the mouse (Subrahmanyam & Greenfield, 2008). The social networking sites have also been very important in educating the public on social and political problems afflicting the society. There are groups of people who have formed social forums and recruited individuals with like-minded views on the social and political events in the country. Members would be easily reached through the internet and topics as well as current affairs discussed. These forums have been quite helpful in bringing change in the political and social arenas in our country. It is the emergence of the internet as a political tool that some countries like the Myanmar, Iran and China have censored its usage among their citizens. These countries have restricted contents of political and religious materials that are accessible to their citizens (Shapiro, 1999). Again, a new internet phenomenon has emerged reshaping the politics and political activities in many countries around the global. What has been referred to as the internet activism has caught on in many countries and political players and citizens alike have embraced internet to win masses into their camps and political groupings (Tolbert, & McNeal, 2003). The current United States president Barrack Obama owes much of his political success to the internet. He amassed overwhelming campaign funds that enabled him outmuscle his opponents in the 2008 elections simply by recruiting a greater mass of followers through the internet. The citizens who were eager for change contributed wholeheartedly to this cause through internet donation. What was most remarkable was the overwhelming following Obama was able to attract over a short period of time in politics. Those who contributed included even non-Americans, who found it easier because of the internet. The internet has also provided leisure activities to its users through social entertainment sites. Currently, there are a number of forums that provide games, videos, and cartoons to entertain internet users. The internet has also enabled easy access to news and information. People these days are able to watch and listen to news, book for vacations, get information on weather and many other things of their interest. There are also thousands of blog sites that have not only provided a platform of communication but have enabled most people to interact by sharing views on various happenings around them. The blog sites have also become political tools most citizens use to lobby people onto their way of thinking (Rodgers, 2003). During the early stages of its development, in the early 1990s, the digital technology led to what many considered internet-euphoria. Many optimists believe it was the new dawn to mankind’s participation in social, political as well as economic spheres in his society. These euphoric evaluation has somewhat changed over the years as more people are now becoming more aware of the dangers technological advancement may pose to the society (Engel, & Keller, 2000). There is the issue of lack of internet safety as the social networking sites have proved to be. The critics of internet claim that it may increase cyber thefts or deceits because one may be able to steal one’s identity especially from the social networking sites. The challenges posed by the internet to the political activities have been cited as some propaganda wars between nations which may spill over into real battles (Tolbert, & McNeal, 2003). Conclusion The internet has profound altered our societal operation both in political and social spheres. The citizens will continue to access vital information that would eventually empower them which in turn will reshape the politics and political class that have long governed with their interest-based policies. Again, the internet has proved to be a better social tool in our society because it has made interaction easier than before. However, there are a few challenges that must be overcome to make it safer for every user.

Stress and how to reduce it

Nowadays, more and more people are concerned about dealing with stress effectively. Stress is defined as a state of mental tension and worry caused by problems in your life or work. Stress is also a normal physical response to events that make you feel threatened or upset your balance in some way. Stress can come from any situation or thought that makes you feel frustrated, angry, nervous, or anxious. What makes people stress? There are many common causes of stress, such as major life changes, Jobless, relationship difficulties, financial problems,†¦ c. In my opinion, stress is caused by the follwing reasons. Firstly, as we know that modern life is full of deadlines, and demands so you usually try to obtain everything. For example, in order to reach a higher position in career or to earn more and more money, you pay more hours in a day and more days in a week for work. The above demands and targets make you feel pressured. Secondly, life of modern people, especially life of thos e who live in big cities is built by a large number of plans and schedules.It is ery well if everything happens smoothly. But in fact, your arranged plans or schedules do not happen as what you expect. Therefore, you may immediatly fall into the status of stress. There are many ways to reduce stress. It depends on the manner that you choose. Firstly, let's start a new day in full of energy by a meditation exercise. Research suggests that daily meditation may alter the brain's neural pathways, making you more resilient to stress. A few minutes of practice per day can help ease anxiety. Secondly, let breathe deeply.Give yourself 5 – minute break from whatever is bothering you and focus instead on your breathing . Thirdly, pause thinking about work in a few minutes, sit down and have breakfast with your tiny family or your collegues. Talking some funny stories to others is the great way to reduce stress. Finally, let you be in present. You rush through dinner, hurry to your next appointment, race to finish one more thing on your agenda. Now try something different: Slow down. Take 5 minutes and focus on only one behavior with awareness.Notice how the air feels on your face when you're walking and how your fit feels hitting the ground. Enjoy the texture and taste of each bite of food as you slowly chew. When you spend time in the moment and focus on your senses, step by step, you can feel the tension leave your body. Totally speaking, stress is not good for our life. the method of reducing stress is various. You should choose the ways which is suitable with you and make you feel leisured. Stress and how to reduce it.

A Late Aubade

A person praises other of his daily activities and says that he does not waste his time and he utilizes his time in useful activities. He then asks him to bring them some eatables.Paraphrase:Now you could be seated in a carrel and turning rotten page or mounting in a caged lift that was moving toward Ladies’ Apparel. You could be sowing in a rough field of salvia while wearing rubber gloves or contemplating over a series of thought of somebody’s love with a disappointing head. Or you are helping a dejected setter to nurse back to health or paying heed to an unwelcoming lecture on Schoenberg's serial technique.1Is this nit something superior?Consider the whole time you are not dissipating and would not be bothered to throw away. Express gratitude to God that such things are not of your flavor. Take into account the time you have by a woman’s calculations and you who had somewhat lazed in bed and kiss, may use your thought and time for this than something else. You declare that it is about midday?If so, time takes wings and I feel no want to repeat the flowery topic of years old poetry. If you have to leave, stay for a short time and after that move downward and fetch some ice-cold white wine with some blue cheese, crackers and some amount of excellent reddish pears. Â  

Fund Managers, Intangibles, and Private Disclosure Essay

Fund Managers, Intangibles, and Private Disclosure - Essay Example Intangibles come in many different forms and nature. Example of these includes structural capital, human capital and relational capital. In the present case, however, intellectual capital is the only intangible that is mentioned. A large extent, it can be said that this is so because the intellectual capital of the present company is made up of an embodiment of all the components of intangibles. What is more, given any market value, intellectual capital is believed to be made up of the difference in the market value and tangible assets possessed by the company. Therefore, because the core component of cash input in the case was share price, the intellectual capital was named as the only intangible to represent all difference that would come from the share price and tangible assets. One critical condition that can be used to judge whether the meeting constitutes insider information or not has to do with whether or not the information given can provide any form of financial advantage in the trading of shares of companies. From this perspective, since the meeting with the fund manager involved information on how value arose and how efforts can be put in place to ensure that in future dealings, more value arose from the intangibles, this advantage could be described as insider information. If for nothing at all, the information that was received was a non-public fact and not accessible to all other players in the share trade business. Ideally, because the overall income of the fund manager is determined by a ratio of the overall fund average asset, it would be said that the insider information was going to benefit the fund manager. This is because he was going to be put in a position where he was going to have better strategies put in place to manage the portfolio of trading activities and consequently see a higher rise in the fund’s average assets.